Earle was the first female chief scientist of the U.S. National Oceanic and Atmospheric Administration and the chairperson of Mission Blue. Mission Blue inspires action to explore and protect the ocean. Mission Blue is uniting a global coalition to inspire an upwelling of public awareness, access, and support for a worldwide network of marine protected areas. She is an oceanographer, explorer, author, and lecturer with experience as a field research scientist, government official, and director for several corporate and non-profit organizations. Earle gained a large amount of publicity when she was featured in Seaspiracy(2021), a Netflix Original documentary by British filmmaker Ali Tabrizi. In a discussion at the Good Food Conference in California, Earle warns of disappearing fish stocks, and that while coastal people"s diets have included seafood for centuries, the commercial fishing industry no longer makes sense and encourages transitions to plant-based diets as a solution.